One of the two main programs of the Human Proteome Project is the Biology/Disease-driven Human Proteome Project (B/D-HPP). It provides
a framework for the coordination of biology- and diseased-based research group contributions to the HPP as described in
Aebersold et al. (2013) in JPR, 12, 23-27 and Aebersold et al. (2014) in Proteomics
(PDF) (highlights of B/D-HPP workshops in Yokohama).
Several groups have begun to assemble prioritized lists of proteins relevant to several different diseases and biological systems and have made them publicly accessible, including popular protein lists for cardiovascular, cerebral, hepatic, renal, pulmonary, and intestinal systems in Lam MP, et al, J Proteome Research July 19, 2016.
Recent key publications:
Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ Systems
Lam MP, Venkatraman V, Xing Y, Lau E, Cao Q, Ng DC, Su AI, Ge J, Van Eyk JE, Ping P.
J Proteome Res. 2016 Jul 19
Prioritizing Proteomics Assay Development for Clinical Translation
Lam MP, Venkatraman V, Cao Q, Wang D, Dincer TU, Lau E, Su AI, Xing Y, Ge J, Ping P, Van Eyk JE.
J Am Coll Cardiol. 2015 Jul 14;66(2):202-4
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