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Overview:

The Human Proteome Project (HPP) is an international project organized by the Human Proteome Organization (HUPO) that aims to revolutionize our understanding of the human proteome via a coordinated effort by many research laboratories around the world. It is designed to map the entire human proteome in a systematic effort using currently available and emerging techniques. Completion of this project will enhance understanding of human biology at the cellular level and lay a foundation for development of diagnostic, prognostic, therapeutic, and preventive medical applications.

Three Pillars:

The three pillars of the HPP are Mass Spectrometry (MS), Antibodies (Abs), and the Knowledgebase (KB). These three pillars form the foundation upon which the chromosome-based HPP and the biology/disease HPP are conceived.

Chromosome-based Human Proteome Project (C-HPP)

The chromosome-based HPP aims to expand our understanding of the human proteome with a focus on expanding the understanding of each and every gene on each chromosome. Additional information is available at the C-HPP portal.

Biology/Disease Human Proteome Project (B/D-HPP)

The biology/disease-based HPP aims to expand our understanding of the human proteome with a focus on important biology research aspects and ongoing disease-focused research.

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